Cambridge Infectious Diseases People

Name:

Daniel Horton MA, VetMB, MSc, MRCVS

Position(s):

CIDC Junior Fellow, PhD student

Email:

d.horton@vla.defra.gsi.gov.uk

Tel.:

+44 (0) 1223 764961

Research description

In collaboration with the Rabies and Wildlife Zoonosis Group at the Veterinary Laboratories Agency (Weybridge), we are quantifying the global antigenic variation among lyssaviruses using cross neutralisation studies and antigenic cartography. The antigenic maps produced allow comparison of genetic and antigenic evolution and provide the potential to predict the neutralisation titre of sera against diverse lyssaviruses. In addition, I collaborate with CIDC colleagues investigating antigenic and genetic evolution of Equine influenza viruses(Nicola Lewis) and the disease dynamics of lyssaviruses in West African fruit bats( David Hayman).

Background

1999 MA Zoology, Cambridge University
2002 Vet MB, Cambridge University
2002-2004 Mixed and exotic animal private veterinary practice, West Sussex, UK
2004-2005 MSc Wild Animal Health, Royal Veterinary College/Institute of Zoology, London
2005-2006 First and second opinion exotic animal veterinary practice (locuming), UK
April 2006 Joined CIDC as a Junior Fellow

Main collaborators

Dr James Wood, Nicola Lewis, David Hayman, CIDC
Professor Derek Smith, Department of Zoology, Cambridge University
Professor Tony Fooks, Dr Lorraine McElhinney, Rabies and Wildlife Zoonoses Group, Veterinary Laboratories Agency, Weybridge
Dr Charles Rupprecht and Dr Ivan Kuzmin, Centers for Disease Control and Prevention, Atlanta, USA
Professor Albert Osterhaus, Erasmus Medical Centre, Rotterdam, NL

Key publications since 2001

Garcia, G., Cunningham, AA., Horton, DL., Garner, TWJ., Hyatt, A., Hengstberger, S., Lopez, J., Ogrodowczyk, A., Fenton, C. and Fa, JE. Mountain chickens Leptodactylus fallax and sympatric amphibians appear to be disease free on Montserrat. Oryx 41(3) 398-401 (2007)
Hayman DTS, Fooks AR, Horton D, Suu-Ire R, Breed AC, Cunningham AA, et al. Antibodies against Lagos bat virus in megachiroptera from West Africa. Emerg Infect Dis In Press