Selective activation of Pattern Recognition Receptors to enhance host protective immunity against infection.
Supervisor - Prof Clare Bryant
I completed my undergraduate degree at the University of Exeter, before being accepted onto the Wellcome Trust 1+3 PhD programme in Infection and Immunity. My MRes rotations were split between CIMR, MRC/Hutchison Research Centre and the Vet School, where I have chosen to remain for my PhD.
Subject groups/Research projects
The emergence of antibiotic resistance, coupled with the lack of an efficient vaccine means Salmonella infections are still a huge problem the developing world; development of a suitable vaccine would be a significant contribution to disease control.
My project aims to identify a modified strain of Salmonella enterica serovar Typhimurium (STm) which selectively activates host Pattern Recognition Receptors to initiate a strong Th1 immune response.