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Department of Veterinary Medicine

Cambridge Veterinary School

Studying at Cambridge

 

Alessandra Bittante

Alessandra Bittante

Selective activation of Pattern Recognition Receptors to enhance host protective immunity against infection.

Supervisor - Prof Clare Bryant


Biography:

I completed my undergraduate degree at the University of Exeter, before being accepted onto the Wellcome Trust 1+3 PhD programme in Infection and Immunity. My MRes rotations were split between CIMR, MRC/Hutchison Research Centre and the Vet School, where I have chosen to remain for my PhD.

Subject groups/Research projects

Infection and Immunity:

Research Interests

The emergence of antibiotic resistance, coupled with the lack of an efficient vaccine means Salmonella infections are still a huge problem the developing world; development of a suitable vaccine would be a significant contribution to disease control.

My project aims to identify a modified strain of Salmonella enterica serovar Typhimurium (STm) which selectively activates host Pattern Recognition Receptors to initiate a strong Th1 immune response.

Keywords

  • Salmonella enterica
  • Adaptive immunity
  • Vaccines
  • Pattern Recognition Receptors