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Department of Veterinary Medicine

Cambridge Veterinary School

Studying at Cambridge

 

Charlotte Palmer

Charlotte Palmer

Exploring Candidate Genes Driving Metastasis in Canine and Human Osteosarcoma

Supervisor: Dr Matthew Allen


Biography:

2015 – Present

PhD Veterinary Sciences (Oncology)

Surgical Discovery Centre

School of Veterinary Medicine

University of Cambridge

 

2014-2015

MPhil Medical Sciences (Oncology)

Cancer Research UK Cambridge Institute

University of Cambridge

 

2011-2014

BSc (Hons) Biomedical Sciences

University of Plymouth

 

Subject groups/Research projects

Genetics and Oncology:

Research Interests

My research goals are to understand the molecular mechanisms that drive the growth and spread of paediatric musculoskeletal tumours such as osteosarcoma (human and canine), Ewing’s sarcoma (human) and rhabdomyosarcoma (human). 

 

Of specific interest is the common prevalence of osteosarcoma among higher breed canines. I am utilizing a comparative translational model of osteosarcoma disease progression in both humans and dogs via both cellular and in vivo model systems. My aim is to search for candidate genes which control the pathogenic progression of lung metastasis from sites of primary malignancy, and to identify risk associated biomarkers in metastatic disease.

By identifying these factors we hope to develop safe and selective treatments to target tumour progression within bone.

Keywords

  • Osteosarcoma
  • Metastasis
  • Bone

Collaborators