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Department of Veterinary Medicine

Cambridge Veterinary School

Studying at Cambridge

 

Dr Srishti Gupta

Biography:

Srishti Gupta completed her B.Sc. in biotechnology from the University of Bangalore (India) before moving to Cambridge in 2010.  She was enrolled in a PhD programme under Professor Chris Lowe and Dr. Graham Christie’s supervision at the Department of Chemical Engineering and Biotechnology on examining structure-function relationships of the receptor proteins involved in the bacterial spore germination process.  She then joined the bacterial infection group, headed by Professor Duncan Maskell and Dr. Andrew Grant, just after completing her doctorate in the summer of 2014.  Her current research mainly focuses on identifying novel molecular mechanisms underlying Campylobacter jejuni biology and pathogenesis.

 

Subject groups/Research projects

Infection and Immunity:

Departments and Institutes

Cambridge immunology network:

Research Interests

As a molecular microbiologist, I have a keen interest towards understanding interaction of pathogenic bacteria with the host and their survival in the environment at a molecular level.  My current work focuses on identifying genetic candidates for effective control of Campylobater in poultry and farm.

Keywords

  • Molecular Biology
  • Bacillus
  • Campylobacter jejuni
  • Protein purification
  • Protein analysis
  • Cloning
  • Pathology

Key Publications

Cruz-Mora J, Pérez-Valdespino A, Gupta S, Withange N, Kuwana R, et al. (2015) The GerW Protein Is Not Involved in the Germination of Spores of Bacillus Species. PLoS ONE 10(3): e0119125. doi:10.1371/journal.pone.0119125

 A. Ramirez-Peralta*, Gupta, S.*, X. Y. Butzin, B. Setlow, G. Korza, M. A. Leyva- Vazquez, G. Christie, and P. Setlow. 2013. Identification of new proteins that modulate the germination of spores of Bacillus species. Journal of Bacteriology. 195:3009-3021. (*contributed equally to this work)

 Gupta, S., F. I. Üstok, C. L. Johnson, D. M. Bailey, C. R. Lowe, and G. Christie. 2013. Investigating the functional hierarchy of Bacillus megaterium PV361 spore germinant receptors. Journal of Bacteriology. 195:3045-3053.