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Department of Veterinary Medicine

Cambridge Veterinary School

Studying at Cambridge


Charlotte Macleod

Charlotte Macleod

Title: The affect of aeroallergens on toll-like receptor signalling.

Supervisor: Professor Clare Bryant


Bachelor degree in Natural Sciences from Cambridge University (2013).

Master of Research in infection and immunity Degree from Cambridge University (2014).

I am a PhD student on the Wellcome Trust Infection and Immunity 4 year PhD programme.

During my masters year I worked with Dr. Alison Condliffe on PI3Ks in airway epithelial cells.  I then worked in Professor Klenerman’s lab using single molecule imaging to investigate the behaviour of Mal, an adaptor protein of Toll-like receptor (TLR)-4.  For my third rotation I worked in Professor Wicker’s lab, looking at the affect of IL-7 on naïve CD4+ T cells. 

I am a PhD student in Professor Clare Bryant’s lab where I am investigating the effects that aeroallergens have on TLR signalling.

Subject groups/Research projects

Infection and Immunity:

Research Interests

1. The affect of aeroallergens on TLR signalling

2. How this relationship can be manipulated to alleviate disease symptoms


  • Allergies
  • Innate Immunity
  • Toll-like receptors
  • TLR4

Collaborators outside this directory

Key Publications

Achouri S, Wright JA, Evans L, Macleod C, Fraser G, Cicuta P, Bryant CE. 2015 The frequency and duration of Salmonella–macrophage adhesion events determines infection efficiency. Phil. Trans. R. Soc. B 370: 20140033.