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Selection of Diseases

At present the site is restricted to diseases that have been documented in the peer reviewed scientific literature or through breed or disease registries. To be included a disease must either show a clearly familial pattern of occurrence or a clear breed predispostion, as evidenced by a markedly increased odds ratio (OR > 5, or as stated in the table) of the disease occurring in that breed, when compared with the general dog population. For a number of commoner defects (hip dysplasia, elbow luxation and some others) which occur in many breeds, we have arbitrarily chosen to record the 20 breeds with the highest breed prevalence as recorded in open registries. Hence, the lists of diseases are necessarily incomplete - and the level of occurrence of each listed disease varies from common to very rare.

Note that this site is designed to be an initial guide for those who want to know more about a breed or a disease. It contains disease listings and short descriptions; genetic and molecular genetic summaries where known; and entry points to the literature on each disease. It is written in fairly specialist language, although accompanied by very short simplified summaries.

The Inherited Diseases in Dogs Database is compiled by David Sargan. Publications referring to this site should cite Sargan, D.R. IDID: inherited diseases in dogs: web-based information for canine inherited disease genetics. Mamm Genome. 2004 Jun;15(6):503-6.

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There is now no direct access from JJ Thompson Avenue. Access is now from Charles Babbage Road.

The 2020 Marjory Stephenson Prize is awarded to Professor Julian Parkhill FRS, from the Dept of Veterinary Medicine, University of Cambridge.

Professor Parkhill is known for his research on bacterial genomes, which he has worked on since the very earliest days of genomics. Initially analysing reference genomes for many important human and animal pathogens, his group moved on to comparative genomics and subsequently large-scale population genomics, as new technologies developed. Read more of this story on https://www.staff.admin.cam.ac.uk/awards/marjory-stephenson-prize

 

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