Senior Lecturer in Epidemiology
I am an infectious disease epidemiologist, based in the Disease Dynamics Unit. I obtained my first degree in Human Sciences from the University of Oxford before completing an MSc in Communicable Disease Epidemiology at the London School of Hygiene and Tropical Medicine. My PhD, based jointly at LSHTM and the Health Protection Agency, examined the impact of vaccination against group C meningococcal (MenC) disease. I worked at the University of Bristol before moving to Cambridge at the start of 2013. I currently hold honorary positions at the University of Bristol and Public Health England.
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My research concentrates on understanding the epidemiology of vaccine-preventable diseases and the impact of immunisation. The majority of my work is on meningococcal infection, but I am also involved in research on pneumococcus, group B streptococcus, rotavirus and human papillomavirus. I use a range of methods including analysis of large databases, systematic reviews, prospective clinical/ field studies, health economics, seroprevalence studies and mathematical modelling. I am most interested in applying these methods to research questions of direct relevance for vaccine policy.
I work with the African Meningococcal Carriage Consortium (MenAfriCar), a global research effort to study how meningococcal meningitis is spread in Africa, and to document the impact of a new meningitis vaccine (MenAfriVac) on reducing transmission. Our study in Chad has shown that MenAfriVac has had a dramatic impact on disease and carriage in a region experiencing a group A epidemic.
I have supervised 4 PhD students to successful completion at the University of Bristol.
MenAfriCar Consortium. The diversity of meningococcal carriage across the African meningitis belt and the impact of vaccination with a group A meningococcal conjugate vaccine. J Infect Dis 2015. doi: 10.1093/infdis/jiv211
Christensen H, Trotter CL, Hickman M, Edmunds WJ. Re-evaluating the cost-effectiveness of universal ‘MenB’ (Bexsero) vaccination in England: a modelling study. BMJ 2014 349 doi: http://dx.doi.org/10.1136/bmj.g5725
Daugla DM, Gami JP, Gamougam K, Naibei N, Mbainadji L, Narbé M, Toralta J, Kodbesse B, Ngadoua C, Coldiron M, Ferman F, Page A-L, Djingarey M, Hugonnet S, Harrison OB, Rebbetts LS, Tekletsion Y, Watkins ER, Caugant DA, Chandramohan D, Hassan-King M, Manigart O, Nascimento M, Woukeu A, Trotter C, Stuart JM, Maiden MCJ, Greenwood B. The impact of a serogroup A meningococcal conjugate vaccine (PsA-TT) on serogroup A meningococcal meningitis and carriage in Chad. Lancet 2014.383:40-7
Irving T, Blyuss K, Colijn C, Trotter CL. Modelling meningococcal meningitis in the African meningitis belt. Epidemiol & Infect 2012 May;140(5):897-905.
Rozenbaum M, van Hoek AJ, Fleming D, Trotter CL, Miller E, Edmunds WJ. Cost-effectiveness of vaccinating risk groups in England against invasive pneumococcal disease using the 13 valent pneumococcal vaccine: an economic analysis. BMJ. 2012 345:e6879
Christensen H, May MT, Bowen L, Hickman M, Trotter CL. A systematic review of meningococcal carriage by age. Lancet Infect Dis 2010, 10:853-61
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