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Department of Veterinary Medicine

Cambridge Veterinary School

Studying at Cambridge

 

Emilia Liana Falcone

Emilia Liana Falcone

Colitis in chronic granulomatous disease: mechanisms and therapeutic targets in inflammatory bowel disease

Supervisors: Prof. Clare Bryant (University of Cambridge) and Dr. Steven Holland (NIH)


Biography:

1999-2002:  BSc, Anatomy and Cell Biology (Major), Music (Minor), McGill University, Montreal, QC, Canada

2002-2007: MSc, Experimental Medicine, McGill University, Montreal, QC, Canada

2003-2007: MDCM, McGill University School of Medicine, Montreal, QC, Canada

2007-2010: Residency, Internal Medicine, Tufts Medical Center, Boston, MA, USA

2010-present: Fellowship, Infectious Diseases, National Institutes of Health (NIH), Bethesda, MD, USA

2013-present: PhD, Veterinary Medicine, University of Cambridge, UK

Subject groups/Research projects

Infection and Immunity:

Departments and Institutes

National Institute of Health:

Research Interests

-Host-pathogen interactions in chronic granulomatous disease

-Role of innate immunity and reactive oxygen species in inflammatory bowel disease

-Study of the interplay between the intestinal microbiome and mucosal immune system in mice and humans with chronic granulomatous disease colitis

Keywords

  • Chronic granulomatous disease
  • Microbiome
  • NADPH Oxidase
  • Innate Immunity
  • Reactive oxygen species

Collaborators

Key Publications

Falcone EL, Holland SM.  Invasive fungal infection in chronic granulomatous disease: insights into pathogenesis and management.  Curr Opin Infect Dis. 2012 Dec;25(6):658-69.

Falcone EL, Zelazny AM, Holland SM.  Rothia aeria neck abscess in a patient with chronic granulomatous disease: case report and brief review of the literature.  J Clin Immunol. 2012 Dec;32(6):1400-3. 

Falcone EL, Hanses S, Stock F, Holland SM, Zelazny AM, Uzel G. Streptococcal infections in patients with chronic granulomatous disease: case   report and review of the literature.  J Clin Immunol. 2012 Aug;32(4):649-52.