Within-host bacterial population dynamics
Supervisor: Dr Olivier Restif
2016 – present: PhD in Veterinary Medicine, University of Cambridge, UK
2013 – 2014: MSc in Biomedical Science, University of Brighton, UK
2007-2011: BSc in Plant Biotechnology, University of Nottingham Malaysia Campus, Malaysia
Subject groups/Research projects
My research looks into the effect that heterogeneity has on within-host bacterial infection dynamics. This question will be explored mainly by way of models that take into account heterogeneous populations (bacteria and macrophages alike), and observe their impact on current understanding of infection dynamics in vivo. These models will be motivated by the recent surge in experimental data available on bacterial infections in vivo, with an emphasis on Salmonella enterica. It is hoped that these models will elucidate exploitable infection dynamics, which in turn will inform future work on alternative anti-microbial treatments that may not be restricted by the issue of anti-microbial resistance.
I am also interested in exploring the parallels between the within-host environment and a classical ecological system by way of applying current population genetic theories to this notion.