Alborada Professor of Equine and Farm Animal Science
Head of Department
James Wood is interested in taking PhD students.
James Wood is available for consultancy.
James Wood is a veterinary epidemiologist who has worked in Cambridge since 2005, initially joining as Director of the Cambridge Infectious Diseases Consortium, prior to appointment as Alborada Professor of Equine and Farm Animal Science in 2009. He studies the dynamics of emerging infectious diseases, including viral infections of fruit bats in West Africa, focused in Ghana, mammalian influenza, rabies and bovine tuberculosis.
He has an MSc in Epidemiology at the London School of Hygiene and Tropical Medicine (1991) and a PhD from the Open University (1997) which he completed when Head of Epidemiology at the Animal Health Trust. He is an RVC graduate (1988), having also completed a BSc in Physiology at UCL (1985).
Departments and Institutes
My research interests focus on the dynamic processes represented in all infectious diseases, at scales from the cellular and sub-cellular through to the more traditionally studied epidemiological scales of the population and metapopulation. Mathematical modelling and more traditional epidemiological approaches are combined with detailed molecular studies of pathogen and host in a multidisciplinary framework. All studies of any infection must also consider the ecology of the host as well as of the infection itself and its pathogenesis.
I have particular interests in the epidemiological dynamics of various virus infections of humans and other animals, including influenza, African horse sickness, canine rabies and emergent lyssavirus and henipavirus infections and the methods needed to study them. Bovine tuberculosis poses interesting challenges at the interface of science and policy and is an important disease and challenge. Funded studies include the emergence of zoonotic viruses, especially in Africa, transmission dynamics of mammalian influenza viruses and their variants through natural hosts and rabies dynamics. I co-supervise several students working on the dynamics of emergent viral infections in bats, in particular Eidolon helvum, in Ghana.
In addition to my research interests, I am also involved in the Cambridge-Africa programme, which focuses on building links between Cambridge and African Institutions and which aims to strengthen Africa's own capacity for a sustainable research (http://www.cambridge-africa.cam.ac.uk/).
- Prof Andrew Cunningham, Institute of Zoology
- Prof Colleen Webb, Colorado State University
- Professor Melissa Leach, STEPS Centre, IDS, University of Sussex
- Dr Julia Gog, Department of Applied Mathematics and Theoretical Physics, Cambridge
- Profs Prof Tony Fooks and Ian Brown, Animal Health Veterinary Laboratories Agency
- Dr Pablo Murcia, MRC - University of Glasgow, Centre for Virus Research
- Prof Bryan Grenfell, Princeton University
- Profs Paul Kellam, Gordon Dougan and Julian Parkhill, Wellcome Trust Sanger Institute
- Prof Yaa Ntiamoa-Baidu, University of Ghana
- Dr Richard Suu-Ire, Ghana Department of Wildlife and Veterinary Services
- Professor Bryan Charleston, Pirbright Institute
- Dr Richard Newton, Animal Health Trust
- Kamins, AO, Rowcliffe, J.M., Ntiamoa-Baidu, Y.N., Cunningham, A.A., Wood, J.L.N. & Restif, O. (2014) Characteristics and risk perceptions of Ghanaians potentially exposed to bat-borne zoonoses through bushmeat. Ecohealth in press
- Luis, A.D., Hayman, D.T.S., O’Shea, T.J., Cryan, P.M., Turmelle, A., Pulliam, J.R.C., Mills, J.M., Timonin, M., Willis, C., Cunningham, A.A. Fooks, A.R., Rupprecht, C., Wood, J.L.N. and Webb, C.T. (2013) A comparison of bats and rodents as reservoirs of zoonotic viruses: Are bats special? Proc Roy Soc B 280 (1756): 20122753
- Peel, A.J., Sargan, D.R., Baker, K.S., Hayman, D.T.S., Barr, J.A., Crameri, G., Suu-Ire, R.D., Broder, C.C., Lembo, T., Wang, L.F., Fooks, A.R., Rossiter, S.J., Wood, J.L.N.* & Cunningham, A.A.* Continent-wide panmixia of an African fruit bat facilitates transmission of potentially zoonotic viruses Nature Communications 4 2770 | DOI: 10.1038/ncomms3770
- Peel, A.J., Pulliam, J..P., Luis, A.D., Plowright, R.K., O’Shea, T.J., Hayman, D.T.S., Wood, J.L.N., Webb, C.T., Restif, O. (2014) The effect of seasonal birth pulses on pathogen persistence in wild mammal populations. Proc Roy Soc B 281, 20132962
- Baker K.S., Marsh, G., Todd, S., Crameri, G., Barr, .J, Kamins, A.O., Peel, A.C., Yu, M., Hayman., D.T.S., Nagjm, B., Mtove, G., Amos, B., Reyburn, H., Nyarko, E.O., Suu-Ire, R., Murcia, P.R., Cunningham, A.A., Wood, J.L.N., Wang, L.F. (2012) Novel, Potentially Zoonotic Paramyxoviruses from the African Straw-Colored Fruit Bat Eidolon helvum. Journal of Virology 87, 1348-1358
- Peel, A., Baker, K.S., Crameri, G., Barr, J.A., Hayman, D.T.S., Wright, E., Broder, C.C., Fernández-Loras, A., Fooks, A.R., Wang, L.F., Cunningham, A.A., Wood, J.L.N. (2012) Henipavirus Neutralising Antibodies in an Isolated Island Population of African Fruit Bats. PLoS ONE 7 e30346 [PubMed].
- Hayman D. T., Wang L. F., Barr J., Baker K. S., Suu-Ire R., Broder C. C., Cunningham A. A. and Wood J. L. 2011. Antibodies to henipavirus or henipa-like viruses in domestic pigs in Ghana, West Africa. PLoS One, 6: e25256. [PubMed].
- Bovine TB
- Brooks Pollock, E., Conlan, A.J.K., Mitchell, A.P., Blackwell, R., McKinley, T.J. & Wood, J.L.N. (2013) Age-dependent patterns of bovine tuberculosis in cattle. Veterinary Research 44 97 doi:10.1186/1297-9716-44-97
- Godfray, H.C.J., Donnelly, C.A., Kao, R.R., Macdonald, D.W., McDonald, R.A., Petrokofsky, G., Wood, J.L.N., Woodroffe, R., Young, D.B., McLean, A.R. (2013) A restatement of the natural science evidence base relevant to the control of bovine tuberculosis in Great Britain. Proc R Soc B 280: 20131634. htt0070://dx.doi.org/10.1098/rspb.2013.1634
- Conlan, A.J.K., McKinley, T.J., Karolemeas, K., Brooks-Pollock, E., Goodchild, A., Mitchell, A., Birch, C., Clifton-Hadley, R.S. & Wood, J.L.N. (2012) Estimating the hidden burden of bovine tuberculosis in Great Britain. PLoS Comp Bio 8 e1002730
- Influenza and others
- Murcia, P.R., Baillie, G.J., Stack, J., Jervis, C., Elton, D., Mumford, J.A., Daly, J., Kellam, P., Grenfell, B.T., Holmes, E.C. & Wood, J.L.N. (2013) Evolution of equine influenza virus in vaccinated horses. Journal of Virology 87 4768-4771
- Morters, M., McKinley, T.J., Horton, D.L., Cleaveland, S., Schoeman, J.P., Restif, O., Whay, HR., Goddard, A., Fooks, A.R., Damriyasa, I.M. & Wood, J.L.N. (2014) Achieving population-level immunity to rabies in free-roaming dogs in Africa and Asia PLoS Neglected Tropical Diseases in press
- Lo Iacono, G., Robin, C.A. , Newton, J.R., *Gubbins, S., *Wood, J.L.N. (2013) Where are the horses? With the sheep or cows? Uncertain host location, vector-feeding preferences and the risk of African horse sickness transmission in Great Britain. Interface 10 (83)
- Hughes, J., Allen, R.C., Baguelin, M., Hampson, K., Baillie, G.J., Elton, D., Newton, J.R., Kellam, P., Grenfell, B.T., Wood, J.L.N., Holmes, E.C. & Murcia, P.R. (2012) Transmission of equine influenza virus during an outbreak is characterized by frequent mixed infections and loose transmission bottlenecks. PLoS Pathogens 8 (12), e1003081
- Murcia, P.R., Hughes, J., Battista, P. Lloyd, L. Baillie, G.J., Ramirez-Gonzalez, R.H., Ormond, D., Oliver, K., Elton, D., Mumford, J.A., Caccamo, M., Kellam, P., Grenfell, B.T., Holmes, E.C. & Wood, J.L.N. (2012) Evolution of an Eurasian avian-like influenza virus in naïve and vaccinated pigs. PLoS Pathogens 8(5): e1002730
- Mutreja A, Kim DW, Thomson NR, Connor TR, Lee JH, Kariuki S, Croucher NJ, Choi SY, Harris SR, Lebens M, Niyogi SK, Kim EJ, Ramamurthy T, Chun J, Wood JL, Clemens JD, Czerkinsky C, Nair GB, Holmgren J, Parkhill J, Dougan G. (2011). "Evidence for several waves of global transmission in the seventh cholera pandemic." Nature 477(7365):462-5. [PubMed]
- Murcia P. R., Baillie G. J., Daly J., Elton D., Jervis C., Mumford J. A., Newton R., Parrish C. R., Hoelzer K., Dougan G., Parkhill J., Lennard N., Ormond D., Moule S., Whitwham A., McCauley J. W., McKinley T. J., Holmes E. C., Grenfell B. T. and Wood J. L. 2010. Intra- and interhost evolutionary dynamics of equine influenza virus. J Virol, 84: 6943-54. [PubMed].
- Park, A. W., J. M. Daly, N. S. Lewis, D. J. Smith, J. L. Wood and B. T. Grenfell (2009). "Quantifying the impact of immune escape on transmission dynamics of influenza." Science 326(5953): 726-728. [PubMed]
- Grenfell, B.T., Pybus, O.G., Gog, J.R., Wood, J.L.N., Daly, J.M. Mumford, J.A. & Holmes, E.C. (2004) Unifying the epidemiological and evolutionary dynamics of pathogens. Science 303, 327-332 [PubMed]