My research centres on the physiology and pharmacology of mechanosensitive ion channels, with a particular focus on their function in red blood cells and their broader implications for vascular biology. I am especially interested in how these channels contribute to the pathophysiology of inherited blood disorders such as Sickle Cell Disease and Hereditary Xerocytosis.
In my lab, we take a multidisciplinary approach that combines functional studies in primary human erythrocytes with electrophysiology and pharmacological profiling. We collaborate with several biotechnology companies to explore new ways of modulating ion channel activity and to help bridge basic discovery with translational potential.
We are also investigating how alterations in membrane ion transport and phospholipid distribution affect red cell survival, circulation, and interaction with the vascular system. Ultimately, our goal is to deepen our understanding of ion channel biology in health and disease, and to identify new therapeutic avenues through which these insights can be applied.
