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Department of Veterinary Medicine

Cambridge Veterinary School

Studying at Cambridge

 

Chiara Talamonti

Chiara Talamonti

Evaluation of the microenvironment and immune function in histiocytic sarcoma

Supervisor: Dr Barbara Blacklaws


Biography:

 

My first experience in the field of Oncology was during the preparation of my dissertation, at the University of Bologna, under the supervision of Professor Bettini in 2013.

I have since been working in first opinion practice in the United Kingdom while studying towards a certificate in Small Animal Medicine. 

In April 2017 I started an MPhil with Dr Blacklaws and Dr Dobson as my supervisors. I will be studying the particular aggressiveness of histiocytic sarcoma in certain breeds, such as the Flat-Coated Retriever. I will be investigating the influence of microenvironment and of individual immune response on the biological behaviour of the tumour. I will be doing this by analysing the presence of regulatory T cells in peripheral blood by flow-cytometry. The objective is to identify possible therapeutic markers to improve, the otherwise poor, prognosis of this tumour.

 

Keywords

  • Histiocytic sarcoma
  • Flat coated retriever

Key Publications

EGFR, HER-2 and KRAS in Canine Gastric Epithelial Tumors: A Potential Human Model?

Rossella Terragni, Andrea Casadei Gardini, Silvia Sabattini, Giuliano Bettini, Dino Amadori, Chiara Talamonti, Massimo Vignoli, Laura Capelli, Jimmy H. Saunders, Marianna Ricci, Paola Ulivi