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Department of Veterinary Medicine

Cambridge Veterinary School

Studying at Cambridge


Hattie Wright

Hattie Wright

Searching for disease causing mutations in brachycephalic obstructive airway syndrome (BOAS)

Supervisor: Dr David Sargan


I obtained a BSc in Zoology at the University of Reading, where I did my undergraduate research project looking at paedomorphosis and the evolution of the domestic dog. Wanting to continue with this theme whilst being able to apply research undertaken to improve canine health and welfare, I am now working on my MPhil project here at Cambridge with the rest of the BOAS research team.

Subject groups/Research projects

Genetics and Oncology:

Research Interests

I have a broad interest in the science behind the breeding and keeping of domesticated animals and the potential for animal welfare issues. BOAS is a health problem associated with breeds selected for short muzzles, such as pugs and bulldogs. For this project I am interested in improving our understanding of the genetics of BOAS, and currently I am working on assessing mutations associated with brachycephalic skull shape for any correlation with presence and severity of BOAS.




  • BOAS
  • Brachycephalic dogs
  • Conformation-related health problems
  • Disease causing mutations