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Department of Veterinary Medicine

Cambridge Veterinary School
 

Veterinary Clinical Pathology

I am a European specialist in veterinary clinical pathology and run the clinical pathology laboratory. As part of this we have a new initiative to bank spare samples for research. The specialism involves a combination of haematology, cytology, and biochemistry and endocrinology profile interpretations. In clinical pathology I am particularly interested in developing and validating new tests. Current ones include Flow cytometry for leukaemias lymphomas and other diseases, urine biomarkers for early renal disease and cardiac biomarkers.

As a fellow of the Royal College of pathologists I am interested in diagnostic histopathology particularly of laboratory animals and exotic species. I also am interested in haematological changes where they can be evaluated using CBC, Bone marrow aspirate cytology and core biopsy histology with immunocytochemistry/ histology to obtain as complete a picture as possible to aid in diagnosis.

Clinical research interests are multifaceted and collaborative. Current studies include pancreatic disease, liver disease, heart disease and neoplasia.

Biography

After gaining masters and PhD degrees in biochemistry followed by post doctoral research experience I spent many years doing laboratory and animal based medical research and teaching biochemistry to medical students. When I change to veterinary medicine I chose to specialise in clinical pathology and pathology as they are laboratory medicine based specialisms. Academic positions have involved teaching veterinary and graduate students, diagnostic services, laboratory management and clinical related research. During my time in Canada I was fortunate to become involved with many wild life projects, and was able to continue these interests at the Royal Veterinary College with exotic species pets and some zoo animals.

Publications

Key publications: 

Serum Cystatin C Concentrations in Cats with Hyperthyroidism and Chronic Kidney Disease.  Williams TL, Dillon H, Elliott J, Syme HM, Archer J. J Vet Intern Med 07 May 2016

Validation of an automated enzyme immunoassay for the measurement of serum total thyroxine in cats. Williams TL, Archer J. Vet Clin Pathol 45(1):148-153 Mar 2016 

In Vitro Influence of Mycophenolic Acid on Selected Parameters of Stimulated Peripheral Canine Lymphocytes. Guzera M, Szulc-Dąbrowska L, Cywińska A, Archer J, Winnicka A. PLoS One 11(5):e0154429 2016

Evaluation of urinary biomarkers for azotaemic chronic kidney disease in cats. Williams TL, Archer J. J Small Anim Pract 57(3):122-129 Mar 2016

Stability of immunophenotypic lymphoid markers in fixed canine peripheral blood for flow cytometric analysis. Cian F, Guzera M.Frost S vanPouckee S Comazzi S Archer J  Vet.Clin.Path. 43;108-8 2014

The use of flow cytometery for Immunophenotyping lymphoproliferative disorders in cats: a retrospective study of 19 cases Guzera M, Cian F, Leo A, Winnicka A Archer J  Vet.and Comp Oncology early view online 2 June 2014

Inhibition of UDPglucosylceramide synthase in mice prevents Gaucher's disease associated B -cell malignancy Pavlova EV, Archer J, Wang S, Dekker N,Aerts J, Karlsson S, Cox TM, J Path. 235: 113 -25 2015

B cell lymphoma and myeloma in murine Gaucher's disease. Pavlova EV. Wang SZ, Archer J, Aertz J, Karlsson S Cox TM.  J Path 231: 88 -97 2013

Initial evaluation of canine Urinary Cystatin C as a marker of renal function Monti P ,Benchekroun G, Berlato D, Archer J.  J Sml Anim. Pract. 53:254-259 2012

Senior Lecturer in Clinical Pathology

Contact Details

Email address: 
+44 (0)1223 337635
Not available for consultancy

Affiliations

Specialities: 
Person keywords: 
Pancreatic Disease
Heart Disease
Liver Disease
Funding: 
PetSavers