skip to content

Department of Veterinary Medicine

Cambridge Veterinary School

Adverse events in anaesthesia

Although principally a clinician at heart, research has to be at the heart of every academic – questioning is what we are about. In anaesthesia we are relatively lucky as many of the accepted clinical practices are based on opinion rather than scientific principles which means that there are many questions to answer. There is little information about adverse events under anasesthesia and this is one area that the anaesthesia service at Cambridge is trying to increase literature in by documenting the adverse events at this hospital. It is hoped to make this a multi-centre study and eventually a national one. Other areas of interest include examining recovery of horses to provide more data to the evidence base, the benefits of using lidocaine plasters for post operative pain relief, duration of epidural analgesia with the addition of alpha-2 agonists, the effect of obesity on dose requirements for induction of anaesthesia and the optimum dose of ketamine for short field anaesthesia in horses. There is also ongoing collaborative work with surgery and the Department of Engineering assessing respiratory function in small animals.


Key publications: 

 A de Vries, JC Brearley and PM Taylor (2009)

Effects of dobutamine on cardiac index and arterial blood pressure in isoflurane-anaesthetised horses under clinical conditions

Journal of Vet Pharm and Therap 32 (4) : 353-358


Panti, A Bennett, R.C Corletto, F. Brearley, J.C Jeffrey, N Mellanby R.J (2009)

The effect of omeprazole on oesophageal pH in dogs during anaesthesia .

Journal of Small Animal Practice 50(1): 540-544


Clark, L.  Leece, E.A  Brearley, J.C (2012)

Veterinary Anaesthesia and Analgesia 39(5): 472-479

Diabetes mellitus affects duration of action of vecuronium in dogs


McMillan, M.W Seymour, C.J Brearley, J.C (2012)

Journal of Small Animal Practice 53(7); 393-397

Effect of intratesticular lidocaine on isoflurane requirements in dogs


McMillan, M., Brearley, J. (2013)

Veterinary Anaesthsia and Analgesia 40(3); 229-236

Assessment of the variation in American Society of Anesthesiologists Physuical Status Classification assignment in small animal anaesthesia.


Boveri, S., Brearley, J. C., & Dugdale, A. H. (2013).

Veterinary Anaesthesia and Analgesia. 40 (5);449-454

The effect of body condition on propofol requirement in dogs.

Dr Jackie  Brearley
Senior Lecturer in Anaesthesia
Director of studies for Veterinary Medicine at Lucy Cavendish College
Academic Lead in the Pauline Brown Clinical Skills Centre

Contact Details

Email address: 
Available for consultancy


Person keywords: