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Department of Veterinary Medicine

Cambridge Veterinary School

I studied for my BSc in Biology at the University of Bath from 2016-2020, where I developed a keen interest in immunology and infectious disease. During my studies, I completed an industrial placement with Oxford Immunotec from 2018-2019. During this year, I completed routine screening of patient samples for the presence of latent Mycobacterium tuberculosis infection using a T-cell ELISpot immunoassay platform as a diagnostic aid. Following graduation, I joined the Laboratory of Viral Zoonotics, headed by Prof. Jonathan Heeney, at the Dep of Vet Medicine as a research assistant working on universal coronavirus and influenza vaccine development projects. This involved implementing and optimising immunoassays to delineate the immunity of vaccine candidates during animal studies. I am currently completing my postgraduate studies within the lab, alongside my research assistantship, and utilise these skills to elucidate pre-existing cross-reactive immunity between different betacoronaviruses to better inform on the development of broadly protective betacoronavirus vaccines.


Broadly, my main research interests are in improving pandemic preparedness against zoonotic infectious diseases within the context of vaccinology. Specifically, I am interested in understanding the host immune correlates of protection against viral diseases to better inform the development of vaccine candidates.


Key publications: 

Carnell, G. W., Billmeier, M., Vishwanath, S., Sans, M. S., Wein, H., George, C. L., ... & Heeney, J. L. (2023). Glycan masking of a non-neutralising epitope enhances neutralising antibodies targeting the RBD of SARS-CoV-2 and its variants. Frontiers in immunology14.


Nadesalingam, A., Cantoni, D., Wells, D. A., Aguinam, E. T., Ferrari, M., Smith, P., Chan, A., Carnell, G., Ohlendorf, L., Einhauser, S., George, C. L., … & Heeney, J. L. (2021). Paucity and discordance of neutralising antibody responses to SARS-CoV-2 VOCs in vaccinated immunodeficient patients and health-care workers in the UK. The Lancet Microbe2(9), e416-e418


Sampson, A. T., Heeney, J., Cantoni, D., Ferrari, M., Sans, M. S., George, C.L., ... & Carnell, G. (2021). Coronavirus pseudotypes for all circulating human coronaviruses for quantification of cross-neutralizing antibody responses. Viruses13(8), 1579.

Scherer, K. M., Mascheroni, L., Carnell, G. W., Wunderlich, L. C., Makarchuk, S., Brockhoff, M., Mela, I., Fernandez-Villagas, A., Barysevich, M., Stewart, H., Sau Sans, M., George. C.L.., ... & Kaminski, C. F. (2022). SARS-CoV-2 nucleocapsid protein adheres to replication organelles before viral assembly at the Golgi/ERGIC and lysosome-mediated egress. Science advances8(1), eabl4895.

On ResearchSquare: Heeney, J., Vishwanath, S., Carnell, G., Ferrari, M., Asbach, B., Billmeier, M., George, C. L... & Frost, S. (2021). Gene delivery of a single, structurally engineered Coronavirus vaccine antigen elicits SARS-CoV-2 Omicron and pan-Sarbecovirus neutralisation.


Postgraduate Student

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