skip to content

Department of Veterinary Medicine

Cambridge Veterinary School


I completed by bachelor’s degree at the University of Toronto, St. George with a double major in Ecology & Evolutionary Biology and Peace, Conflict & Justice Studies. I also received a minor in Biology, offered jointly with the National University of Singapore.


I am currently a graduate student in the Laboratory of Viral Zoonotics, and Prof. Jonathan Heeney and Dr. Barbara Blacklaws are my supervisors. My research focuses broadly on understanding the transmission of zoonotic viruses and immune correlates of protection. I am studying the transmission of Lassa virus from rodents to humans, as well as the correlates of protection in humans for SARS-Cov-2.


My primary interest is understanding the ways in which humans are exposed to viruses of zoonotic origin, and what viral and immune parameters protect individuals from progressing to disease.


Key publications: 

1. Atti A, Insalata F, Carr EJ, Otter AD, Castillo-Olivares J, Wu M, Harvey R, Howell M, Chan A, Lyall J, Temperton N, Cantoni D, da Costa K, Nadesalingam A, Taylor-Kerr A, Hettiarachchi N, Tranquillini C, Hewson J, Cole MJ, Foulkes S, Munro K, Monk EJM, Milligan ID, Linley E, Chand MA, Brown CS, Islam J, Semper A, Charlett A, Heeney JL, Beale R, Zambon M, Hopkins S, Brooks T, Hall V; SIREN Study Group and the Crick COVID Immunity Pipeline Consortium. Antibody correlates of protection from SARS-CoV-2 reinfection prior to vaccination: a nested case-control within the SIREN study. J Infect. 2022: S0163-4453(22)00535-7. doi: 10.1016/j.jinf.2022.09.004. PMID: 36089104. (IF=38.64).


2. Wells DA, Cantoni D, Mayora-Neto M, Genova CD, Sampson A, Ferrari M, Carnell G, Nadesalingam A, Smith P, Chan A, Raddi G, Castillo-Olivares J, Baxendale H, Temperton N, Heeney JL. Human seasonal coronavirus neutralization and COVID-19 severityJ Med Virol. 2022; 94(10):4820-4829. doi: 10.1002/jmv.27937. PMID: 35705514. (IF=20.59).


3. Cantoni D, Mayora-Neto M, Nadesalingam A, Wells DA, Carnell GW, Ohlendorf L, Ferrari M, Palmer P, Chan ACY, Smith P, Bentley EM, Einhauser S, Wagner R, Page M, Raddi G, Baxendale H, Castillo-Olivares J, Heeney J, Temperton N. Neutralisation Hierarchy of SARS-CoV-2 Variants of Concern Using Standardised, Quantitative Neutralisation Assays Reveals a Correlation With Disease Severity; Towards Deciphering Protective Antibody ThresholdsFront Immunol. 2022 Mar 7;13:773982. doi: 10.3389/fimmu.2022.773982. PMID: 35330908. (IF=8.79).


4. Cantoni D, Mayora-Neto M, Thakur N, Elrefaey AME, Newman J, Vishwanath S, Nadesalingam A, Chan A, Smith P, Castillo-Olivares J, Baxendale H, Charleston B, Heeney J, Bailey D, Temperton N. Pseudotyped Bat Coronavirus RaTG13 is efficiently neutralised by convalescent sera from SARS-CoV-2 infected patientsCommun Biol. 2022; 5(1):409. doi: 10.1038/s42003-022-03325-9.PMID: 35505237. (IF=6.27).


5. Nadesalingam A, Cantoni D, Wells DA, Aguinam ET, Ferrari M, Smith P, Chan A, Carnell G, Ohlendorf L, Einhauser S, George C, Wagner R, Temperton N, Castillo-Olivares J, Baxendale H, Heeney JL; HICC consortium. Paucity and discordance of neutralising antibody responses to SARS-CoV-2 VOCs in vaccinated immunodeficient patients and health-care workers in the UK. Lancet Microbe. 2021; 2(9):e416-e418. doi: 10.1016/S2666-5247(21)00157-9. PMID: 34223399 (IF=86.2).


6. Castillo-Olivares J, Wells DA, Ferrari M, Chan ACY, Smith P, Nadesalingam A, Paloniemi M, Carnell GW, Ohlendorf L, Cantoni D, Mayora-Neto M, Palmer P, Tonks P, Temperton NJ, Peterhoff D, Neckermann P, Wagner R, Doffinger R, Kempster S, Otter AD, Semper A, Brooks T, Albecka A, James LC, Page M, Schwaeble W, Baxendale H, Heeney JL. Analysis of Serological Biomarkers of SARS-CoV-2 Infection in Convalescent Samples From Severe, Moderate and Mild COVID-19 Cases. Front Immunol. 2021; 12:748291. doi: 10.3389/fimmu.2021.748291. eCollection 2021. PMID: 34867975 (IF=8.79).


7. Baxendale HE, Wells D, Gronlund J, Nadesalingham A, Paloniemi M, Carnell G, Tonks P, Ceron-Gutierrez L, Ebrahimi S, Sayer A, Briggs JAG, Ziong X, Nathan JA, Grice G, James LC, Luptak J, Pai S, Heeney JL, Lear S, Doffinger R. Critical Care Workers Have Lower Seroprevalence of SARS-CoV-2 IgG Compared with Non-patient Facing Staff in First Wave of COVID19. J Crit Care Med. 2021; 7(3):199-210. doi: 10.2478/jccm-2021-0018. PMID: 34722923.


8. Storisteanu DM, Pocock JM, Cowburn AS, Juss JK, Nadesalingam A, Nizet V, Chilvers ER. Evasion of Neutrophil Extracellular Traps by Respiratory Pathogens. Am J Respir Cell Mol Biol. 2017; 56(4):423-431. doi: 10.1165/rcmb.2016-0193PS. PMID: 27854516 (IF=7.75).


 Angalee  Nadesalingam

Contact Details

Email address: 
Not available for consultancy


Person keywords: 
Lassa virus
Zoonotic viruses