Liza Hadley

My research explores the role of infectious disease modelling in international outbreak response. We are interested in how mathematical modelling is used by governments, health organisations, and other decision-makers during a health crisis, and whether the process can be improved. Our current study aims to interview modellers and decision-makers in every major country that has used modelling for Covid-19 response, drawing together experiences and lessons learned in time for the next crisis. This project is supervised by Prof Sebastian Funk (LSHTM).

Additionally, I provide mathematical modelling support for key vaccine-preventable disease outbreaks in the UK and globally. Examples include informing MenACWY vaccination strategy by investigating the expected impact of Covid-19 disruption to meningococcal meningitis in the UK, and supporting the World Health Organization's Meningitis Roadmap work by examining optimal outbreak control strategies for pneumococcal meningitis in the African Meningitis Belt.

Supervisors & advisors: Dr Olivier Restif, Prof James Wood, Prof Sebastian Funk, Prof Caroline Trotter, Dr Alex Tasker.

Affiliation & funding: I am jointly affiliated to the University of Cambridge and the London School of Hygiene and Tropical Medicine, and am funded by the Wellcome Trust.

BIOGRAPHY

Before starting my PhD at the University of Cambridge, I completed my Undergraduate Masters in Mathematics at the University of Oxford (2014-2018), and then worked as a Research Assistant at the London School of Hygiene and Tropical Medicine (2019). At LSHTM, I worked in vaccine epidemiology with Profs Mark Jit, Kaja Abbas, and Kiesha Prem, evaluating the impact and cost of one-dose vs two-dose HPV vaccination campaigns.

Publications

Key publications:

Research articles:
•   Published: Hadley, L., Challenor, P., Dent, C., Isham, V., Mollison, D., Robertson, D. A., Swallow, B., Webb, C. R. (2021). Challenges on the interaction of models and policy for pandemic control. Epidemics (37).
•   Published: Hadley, L., Karachaliou Prasinou, A., Christensen, H., Ramsay, M., Trotter, C. (2023). Modelling the impact of Covid-19 and routine MenACWY vaccination on Meningococcal carriage and disease in the UK. Epidemiology & Infection (151).
•   Published: Marion, G., Hadley, L., Isham, V., Mollison, V., Panovska-Griffiths, J., Pellis, L., Scalia Tomba, G., Scarabel, F., Swallow, B., Trapman, P., Villela, D. (2022). Modelling: understanding pandemics and how to control them. Epidemics (39).
•   Published: Prem, K., Choi, Y. H., Bénard, É., Burger, E. A., Hadley, L., Laprise, J., Regan, M. C., Drolet, M., Sy, S., Abbas, K., Portnoy, A., Kim, J. J., Brisson, M., Jit, M. (2023). Global impact and cost-effectiveness of one-dose versus two-dose human papillomavirus vaccination schedules: a comparative modelling analysis. BMC Medicine (21).
•   Submitted to BMJ Global Health: Oliwa, J. N., Guleid, F., Owek, C. J., Maluni, J., Jepkosgei, J., Sim, S. Y., Were, V., Nzinga, J., Walekhwa, A. W., Clapham, H. E., Dabak, S. V., Kc, S., Unduragga, E. A., Hadley, L., Hutubessy, R., Hagedorn, B. L. (2023). A framework to guide the use of mathematical modelling in evidence-based policy decision-making.
•   Awaiting submission: Hadley, L., Soeters, H., Cooper, L., Fernandez, K., Trotter, C. (2023). Modelling outbreak control strategies for pneumococcal meningitis in the African meningitis belt.
•   Awaiting submission: Adams, L., Karachaliou Prasinou, A., Hadley, L., Ramsay, M., Campbell, H., Trotter, C. (2023). Estimating the potential number of cases prevented by infant and toddler immunisation with a MenACWY vaccine.
• In progress: Hadley, L., Funk, S., Rich, C., Restif, O. (2023). Advancing the use of infectious disease modelling in national and international outbreak response: a global analysis.

Conference proceedings:
• Published: Hadley, L., Karachaliou Prasinou, A., Christensen, H., Ramsay, M., Trotter, C. (2023). Modelling the impact of Covid-19 and routine MenACWY vaccination on Meningococcal carriage and disease in the UK. International Journal of Infectious Diseases (130).

Teaching and Supervisions

Teaching:

I currently have one research assistant and supervise two undergraduate Mathematics courses. I also co-run the St John's Women in Mathematics Summer School.

I have previously assisted with teaching for the MPhil in Population Health Sciences.