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Department of Veterinary Medicine

Cambridge Veterinary School
 

Quantitative tools for One Health research in infectious diseases

I lead a diverse, multi-disciplinary team working on a range of infectious diseases within a One Health framework. We use mathematical and statistical models to design, analyse and interpret empirical studies of infectious disease dynamics with a focus on zoonoses. I collaborate with veterinary epidemiologists who track diseases in animals, anthropologists who investigate social practices around disease risks, and ecologists who monitor wildlife responses to global changes. I have also led and contributed to several projects on bacterial infection dynamics and antimicrobial resistance.

Recent and current projects include:

  1. Henipaviruses and filoviruses in tropical bats.
  2. Epidemiology and control of dog rabies.
  3. Mapping multi-drug resistance in bacteria.

Biography

  • Engineering Degree, Ecole Polytechnique 1999
  • Master's Degree in Ecology, Universite Paris VI 2000
  • PhD in Ecology, Universite Paris VI 2000-2003, supervised by Prof. Jacob Koella
  • Royal Society University Research Fellowship 2008-2016
  • Alborada Lecturer in Epidemiology 2013-2019
  • Alborada Associate Professor in Epidemiology since 2020

Research

1. Zoonotic virus ecology in bats.

The emergence of new viruses from bats in the last 30 years has drawn the attention of a broad scientific community to the ecology and immunology of this diverse group of mammals. We have established a successful international collaboration with Ghana and Australia to study fruit bats, their ecology, their viruses and their interactions with people. My team also investigates some of the challenges posed by zoonotic and emerging diseases (e.g. rabies, hemorrhagic fevers and COVID-19) in low-and-middle-income countries.

Current and former team members: Less Rowe, Maya Juman, Elisa Fesce, Imogen Lindsley, Elinor Jax, Emma Glennon.

Collaborators: Raina Plowright (Cornell University), Andrew Cunningham (Institute of Zoology), Yaa Ntiamoa-Baidu (University of Ghana), Alison Peel (University of Sydney), Emily Nixon (Liverpool University), Julien Cappelle (CIRAD Montpellier), Jason Ladner (Northern Arizona University), James Wood (Cambridge), Charlotte Hammer (Cambridge).

 

2. Control of dog rabies.

I collaborate with veterinarians in rabies endemic countries in Africa and Asia to help them measure the burden of rabies and dog bites with the aim of improving surveillance and prevention.

Current and Team members: Rakesh Chand, Michelle Morters.

Collaborators: Malanga Sambo (IHI Tanzania), Katie Hampson (University of Glasgow). 

 

3. Mapping multi-drug resistance in bacteria.

Antimicrobial resistance (AMR) is a major threat to human and animal health. Multi-drug resistance is a particular concern, and is increasingly reported using genetic (sequencing) or phenotypic (growth inhibition assay) tools. However, analysing and interpreting these complex datasets requires sophisticated and ofter tailor-made computational techniques. We are investigating the epidemiology and evolution of multi-drug resistance in pathogenic, commensal and zoonotic bacterial pathogens in farm animals.

Current and former team members: Andrew Balmer, Ruchita Balasubramanian, Emma Salafsky.

Collaborators: Mark Holmes, Lucy Weinert (Cambridge), Gemma Murray (UCL).

 

Publications

Key publications: 

Google Scholar profile

 

Teaching and Supervisions

Teaching: 
  • Module organiser and examiner for NST Part II Pathology 
  • Lecturer for NST Part IA Mathematical Biology.
  • Lecturer for NST Part IB Mathematical and Computational Biology. 
  • Fellow of the Higher Education Academy (Advance HE)
Research supervision: 
  • Post-docs
    • Elisa Fesce (2021-2023)
    • Elinor Jax (2019-2023)
    • Aaron Morris (2018-2020)
    • Michael Bateman (2015-2017)
    • Romain Garnier (2015-2017)
    • David Price (2015-2017)
    • Anaid Diaz (2012-2016)
    • Alison Peel (2012)
  • PhD students
    • Maya Juman (2023-2026)
    • Liza Hadley (2020-2024)
    • Rakesh Chand (2020-2025)
    • Andrew Balmer (2018-2022)
    • Myrto Vlazaki (2017-2020)
    • Ed Lam (2016-2020)
    • Emma Glennon (2016-2020)
    • Alexandra Kamins (2009-2012)
  • MPhil students
    • Kess Rowe (2025-2026)
    • Emma Salafsky (2024-2025)
    • Imogen Lindsley (2021-2022)
    • Ido Ben Zvi (2020-2021)
    • Ruchita Balsubramanian (2020-2021)
    • John Huber (2017-2018) 
    • Eric Mooring (2013-2014)
    • David Bradley (2014)
    • Lisanne Rens (2012)
    • Alice Wright (2011)

Other Professional Activities

Alborada Associate Professor in Epidemiology
Director of Postgraduate Education
Director of Studies (NST Biology) at Robinson College

Contact Details

Email address: 
+44 (0)1223 764963
Takes PhD students
Available for consultancy

Affiliations

Classifications: 
Local Affiliations: 
Person keywords: 
Antibiotic resistance
Bayesian Methods
Ecology
Mathematical modelling
Salmonella enterica
Host-Pathogen Interaction
Antimicrobial resistance
Evolution
Microbiology
Epidemiology
Infectious disease dynamics
Bats
Zoonoses
Bacteriology
Disease Ecology
Evolutionary biology
Funding: 
National Science Foundation
Royal Society
The Alborada Trust
Medical Research Council
Biosciences and Biotechnology Research Council